Analog front end for high-speed end equipments like phased-array radars: wireless communication testers: and electronic warfare require synchronized: multipletransceiver signal chains. Each transceiver signal chain includes high-speed: analog-to-digital converters (ADCs): digital-to-analog converters (DACs): and a clock subsystem. The clock subsystem provides low noise sampling clocks with precise delay adjustment to achieve lowest channel-to-channel skew and optimum system performance like signal-to-noise ratio (SNR): spurious free dynamic range (SFDR): IMD3: effective number of bits (ENOB): and so forth. This reference design demonstrates multichannel JESD204B clocks generation and system performance with AFE7444 EVMs. Channel-to-channel skew better than 10 ps achieved with 6 GSPS/3 GSPS DAC/ADC clocks up to 2.6-GHz radio frequencies and system performance like SNR and SFDR are comparable to the AFE7444 data sheet specifications.