Temperature-sensing applications that use a thermocouple (TC) require an accurate local temperature sensor to achieve high accuracy. Solutions for design challenges such as cold-junction compensation (CJC) or including an ultra-low power TC analog front-end are highlighted and addressed in this reference design. Performance in terms of power consumption and accuracy is optimized for accurate 4 to 20 mA sensors while also demonstrating the performance of different CJC and TC front-end implementations.